Immunomodulatory Agents and Risk of Postpartum Multiple Sclerosis Relapses
نویسندگان
چکیده
منابع مشابه
Immunomodulatory agents and risk of postpartum multiple sclerosis relapses.
OBJECTIVE To determine whether treatment with an interferon beta or glatiramer acetate shortly after delivery reduces the otherwise increased risk of postpartum relapses of multiple sclerosis. METHODS In a retrospective cohort of 112 women with multiple sclerosis and live births from Kaiser Permanente Southern California, complete medical and pharmacy records of the mothers and infants were r...
متن کاملExclusive breastfeeding and the risk of postpartum relapses in women with multiple sclerosis
Introduction: Multiple Sclerosis (MS) is primarily a disease of women in their childbearing years. Risk for postpartum relapse is increased in the first 3 months after delivery. Previous studies of breastfeeding and postpartum relapse showed little or no benefit, but none examined exclusive breastfeeding. Methods: In this review article, electronic searches were undertaken in PubMed, Scholar...
متن کاملVitamin D, pregnancy, breastfeeding, and postpartum multiple sclerosis relapses.
OBJECTIVE To determine whether low levels of 25-hydroxyvitamin D (25[OH]D) contribute to the increased risk of postpartum multiple sclerosis (MS) relapses. DESIGN Prospective cohort study. SETTING Outpatients identified through membership records of Kaiser Permanente Northern California or Stanford University outpatient neurology clinics. PATIENTS Twenty-eight pregnant women with MS. IN...
متن کاملExclusive breastfeeding and the risk of postpartum relapses in women with multiple sclerosis.
OBJECTIVE To determine if exclusive breastfeeding protects against postpartum relapses of multiple sclerosis (MS) and, if so, whether this protection is related to prolonged lactational amenorrhea. DESIGN We conducted structured interviews to assess clinical, menstrual, and breastfeeding history during each trimester and 2, 4, 6, 9, and 12 months postpartum and collected neurological examinat...
متن کاملQuantitative benefit-risk assessment of methylprednisolone in multiple sclerosis relapses
BACKGROUND High-dose short-term methylprednisolone is the recommended treatment in the management of multiple sclerosis relapses, although it has been suggested that lower doses may be equally effective. Also, glucocorticoids are associated with multiple and often dose-dependent adverse effects. This quantitative benefit-risk assessment compares high- and low-dose methylprednisolone (at least 2...
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ژورنال
عنوان ژورنال: The Permanente Journal
سال: 2014
ISSN: 1552-5767
DOI: 10.7812/tpp/13-090